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Browsing by Subject "SIGNALING PATHWAYS"

Now showing items 1-3 of 3

    • The Catabolic Role of Toll-Like Receptor 2 (TLR-2) Mediated by the NF-kappa B Pathway in Septic Arthritis 

      Papathanasiou, I.; Malizos, K. N.; Poultsides, L.; Karachalios, T.; Oikonomou, P.; Tsezou, A. (2011)
      Toll-like receptors (TLRs) are involved in mediating cell activation on stimulation with microbial components. Our objective was to investigate the role of 'PLR-2 mediated by the NF-kappa B pathway in septic arthritic ...

    • Cytokine Effects on Cell Viability and Death of Prostate Carcinoma Cells 

      Chondrogiannis, G.; Kastamoulas, M.; Kanavaros, P.; Vartholomatos, G.; Bai, M.; Baltogiannis, D.; Sofikitis, N.; Arvanitis, D.; Galani, V. (2014)
      We analyzed the effects of IL-13, IFN-gamma, and IL-1 beta on cell viability and death of LNCaP and PC-3 cells and major signaling pathways involved in these effects. Significant increase of LNCaP cell death (apoptotic and ...

    • Regulation of the autophagic machinery in human neutrophils 

      Mitroulis, I.; Kourtzelis, I.; Kambas, K.; Rafail, S.; Chrysanthopoulou, A.; Speletas, M.; Ritis, K. (2010)
      The induction of the autophagy machinery, a process for the catabolism of cytosolic proteins and organelles, constitutes a crucial mechanism in innate immunity. However, the involvement of autophagy in human neutrophils ...